Is it safe to drink alcohol while taking Zoloft? Home › Forums › Ask-A-Doc › Is it safe to drink alcohol while taking Zoloft? Tagged: alcohol, side effects, Zoloft This topic has 0 replies, 1 voice, and was last updated 2 years, 4 months ago by FaceMyDoc. Viewing 1 post (of 1 total) Author Posts July 26, 2021 at 2:31 pm #169050 FaceMyDocKeymaster 21 year old male, takes 100mg Zoloft daily, asks “Is it safe to drink tonight or should I refrain from consuming any alcohol?” Author Posts Viewing 1 post (of 1 total) You must be logged in to reply to this topic. Log In Username: Password: Keep me signed in Log In